Indu Latha
Sanjay Gandhi Postgraduate Institute of Medical Sciences, India
Title: To evaluate the vitamin D levels in infertile females and to study the correlation of vitamin D deficiency with antimmullerian hormone levels in infertile females compared to fertile females
Biography
Biography: Indu Latha
Abstract
Background: In the last few years a growing interest in vitamin D can be observed in various segments of medical field due to findings demonstrating low vitamin D status in the population and its harmful effects on various systems. Vitamin D also plays a vital role in expression of a large number of genes in reproductive tissues implicating a role for vitamin D in female reproduction.
Objective: To evaluate the Vitamin D levels in infertile females to study the correlation of circulating 25-hydroxyvitamin D (25OH-D) levels with serum antimmullerian hormone in infertile females compare to fertile females.
Design: Prospective study was conducted in department of Maternal and Reproductive Health in between 2014-2016 for 2 years.
Patient(s): All infertile females as cases and fertile females as controls were taken after some inclusion and exclusion criteria. 35 patients were taken in each group.
Intervention(s): Serum for 25-hydroxyvitamin D (25OH-D) and AMH with other infertility investigations were taken.
Main Outcome Measure(s): Vitamin D levels in infertile females and correlation between 25OH-D and AMH in vitamin D deficient infertile and fertile females.
Result(s): On analysis of data the Vitamin D deficiency was present in 64% of infertile female’s population. In vitamin D deficient cases (infertile females) the mean for vitamin D was 6.18± 2.09 and for AMH 1.94±1.30. In vitamin D deficient controls (fertile females) the mean for vitamin D was 4.85±3.02 and for AMH 3.47±2.59. There is no significant correlation between vitamin D and AMH levels in these two groups. On comparison of these two groups Vitamin D levels were more lower in control group than cases which was significant (P=0.04) and AMH levels were more lower in cases than control group(P=0.003).
Conclusion(s): In this study, no significant correlation was found in between circulating Vitamin D and antimmullerian hormone levels.