Biography
Biography: Amal A L Mulla
Abstract
Polycystic ovary syndrome (PCOS) is a condition with a range of reproductive and metabolic features that affect 4-18% of reproductive age group, and subsequently affect the quality of life. Underproduction of estrogen and over production of androgen (testosterone, dehydro epiandrsterone and androstendione) by the ovaries can result in a number of additional clinical features, including tiny cysts on the surface of the ovaries and hair and skin symptoms. Women with PCOS and related disorders comprise a large proportion of women undergoing induction of ovulation for infertility therapy. The major reproductive adversity facing these patients is their elevated risk of endometrial cancer. Unopposed estrogen exposure probably contributes to this risk. Women with PCOS who become pregnant are at higher risk than those without PCOS of developing gestational diabetes or suffering a first – trimester spontaneous abortion.